Fortune 500 Pharma Company
Re-architecting
the eTMF application to
Model-view-viewmodel
Industry: Pharma
Services Offered
UI/UX Consulting
App Modernization
App Optimization
Overview
The growth of clinical trials in terms of scope and complexity is transforming the approach to content management in pharmaceutical, as well as biotechnology companies. Electronic Trial Master Files (TMFs) are, therefore, the go-to place for maintaining a central repository for the storage of clinical trial documents for use in regulatory submissions. With the next generation of eTMFs, more advanced technologies and capabilities will be rendered for sure.
Our Client
Our client is a research-based
global biopharmaceutical company headquartered in the USA. With an innovative approach
and global resources, this company is engaged in the discovery, development, and
manufacturing of healthcare products
and vaccines. This involves extensive research, documentation, creation of case studies, and
compilation of data in the
form of images, documents, and other digital content management.
Our client uses eTMF – electronic trial master file for building these documentations for
clinical trials. Celestial has
been instrumental in the eTMF Next-gen project for our client, i.e., upgrading this eTMF
application to use the latest
production version of Ext JS 7.2.
Business Requirements
Revamp the UI of the application
Upgrade the frontend to the latest version of Sencha Ext JS
Re-architecting the application to a modern framework
Celestial’s Solution
The eTMF Next-gen project’s objective was to upgrade the eTMF application to use the latest production version of Ext JS 7.x and to re-architect the application so that it uses the inherent automated functions and features such Sencha CMD, MVVM, as well as proper theming. The existing eTMF application lacked the “Next Generation” TMF capabilities like automated quality checks, proactive monitoring, modeling, and predicting all aspects of records management from the study, design through closeout. We assisted in upgrading the older Ext JS version to the latest which follows the inherent automated functions and features such as Sencha CMD and MVVM.
Ext JS
4.2 to 7.2 version
The eTMF application was upgraded to the latest version of Ext JS with improvements in grid features, data binding, and even faster loading time.
MVVM
Architecture
Re-architected the application to Model-view-viewmodel which resulted in a UI-based design system with improved application productivity, maintainability, flexibility, testability, and reusability.
Automated
Quality checks
The new app offered advanced functionalities such as automated quality checks, eliminating the need for manual QC findings, and providing alerts for low-performing studies and sites.
Architecture
We used Model-view-viewmodel (MVVM) architecture for
this eTMF Next gen project. The best part of
MVVM architecture is
that we can attach multiple views to a single viewmodel.
A new Ext JS 7.2 classic app was created, and their existing code was copied into the correct
folder structure of a MVVM
Ext JS app. During the build, we created a single app under src/main/javascript, with Sencha app
having its artifacts
copied over to the appropriate subfolder under webapps. We had a Single Page Application (SPA)
and each JSP was getting
converted to a proper Ext JS Route and thus the URLs (deep linking) were almost identical.
Technology Used
Outcomes
- Frontend upgraded to latest version of Ext JS
- Brought the application to MVVM architecture
- 85% Performance improvement
- 80% faster loading time
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